VOLUME. 1, ISSUE 2, OCTOBER 2022

Abstract :- An analytical method was developed for the determination of Lutetium in dilute nitric acid medium using high resolution ICP-AES analytical technique. These studies were required for the determination of Lutetium contents in radiopharmaceutical samples. For the patients suffering from cancers, 177Lu DOTA-TATE peptide receptor radionuclide therapy is used. This necessitates the use of 177Lu and obviously the quantification of Lutetium for its efficient application during medical therapy which is used for the preparation of the patients suffering from cancers. Due to short half life of 177Lu of 6.67 days, it is most likely to get added up with Hf, as it is build up on storage, the undesired impurity element. Hence the effect of Hf on the determination of Lu was studied. Subsequently seven actual samples of 177Lu were analysed for Lu contents after taking into account Hf contribution if any.

Author :- V.C. Adya1+*, Arijit Sengupta , Sudipta Chakraborty , K.Vimalnath and S. K. Thulasidas1+1Radiochemistry Division, Radiochemistry Division (former), Radiopharmaceutical
Email:- l: vcadya@rediffmail.com

DOI :     https://doi.org/10.59143/isas.jisas.1.2.MMHI7334

           Pages :- 58-67